What does it mean to be a man? The answer to this question changes radically across time and space. Currently masculinity can be understood variously as a series of cultural constructs, as biologically deterministic, as a set of gendered expectations and assumptions, and more. Normative models of masculinity rely on problematic stereotypes such as emotional unavailability, physical strength and dominance, and inept caregiving. This semester’s Faculty Seminar and Clarke Forum theme explores, in historical, cross-cultural, and contemporary contexts, this many-layered concept of masculinity. Drawing from deeply interdisciplinary perspectives, its explorations will range from historical perspectives on the construction of masculinity, artistic challenges to hegemonic masculinities, neuroscientific and biological studies on the relevance of gender to brain science, and social scientific and policy-oriented work on the prevention, costs, and consequences of toxic masculinity.